Chloroquine retinopathy: is there a safe daily dose?

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Chloroquine Retinopathy Ideal body weight Dr. F.R. Ochsendorf, Department of Dermatology, University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt/M. (Germany) In this journal, Lipsker et al. [1] emphasized the efficacy of the combination of chloroquine and quinacrine for the treatment of resistant cutaneous lupus erythematosus. 20% of their patients (3/15), however, developed abnormalities ...

Incidence of and risk factors for chloroquine and hydroxychloroquine retinopathy in Thai rheumatologic patients

OBJECTIVE To study the incidences of and risk factors for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy in Thai rheumatologic patients. METHODS A retrospective cohort study of 234 rheumatologic patients receiving either CQ or HCQ was conducted. Patients were divided based on whether or not they developed retinopathy as retinopathy-positive or negative groups. Medical records givin...

Chloroquine: consideration of maximum daily dose (3.5 mg/kg ideal body weight) prevents retinopathy.

Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 Revision).

BACKGROUND The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. PATTERN OF RETINOPATHY Although the locus of toxic damage is parafoveal in many eyes, Asian patients often s...

Retinal Toxicity Due to Antimalarials: Frequency and Risk Factors

Objective: To study the frequency of retinal toxicity and associated risk factors in a cohort of patients treated with antimalarials and seen at a tertiary level hospital. Material and methods: Retrospective study of 40 patients treated with antimalarials, who were referred to ophthalmology for the study of retinal toxicity during 2011. Data collection included type of antimalarial prescribed, ...